Aesthefill is a PDLLA collagen stimulator from REGEN Biotech in Korea, supplied as a freeze-dried powder in a single vial. Rather than adding filler, it prompts the skin to build its own collagen, so volume shows up gradually over the months after treatment. It is the deep-placement member of the PDLLA family.
What is Aesthefill?
Aesthefill is poly-D,L-lactic acid (PDLLA) microspheres, reconstituted in clinic before use. The amorphous D,L form reconstitutes faster and spreads more evenly in suspension than crystalline PLLA.
Its particles are larger than those in Juvelook, which suits the deeper plane where support is built.
What is Aesthefill used for?
It suits patients whose skin has thinned across a whole region, not just in one hollow. Because nothing is added, the result does not look filled.
- Cheeks and temples
- Jawline
- Nasolabial folds
- Fine wrinkling around the eyes and mouth from a thinner dermis
How is Aesthefill prepared and placed?
Reconstitute before use and dissolve by gentle swirling, never shaking. Diluent, hydration time, depth and technique follow REGEN Biotech’s instructions in the box; placement is subcutaneous or deep dermal, with post-treatment massage.
Avoid treating active infection, known hypersensitivity, keloid tendency, pregnancy or breastfeeding. Aesthefill is for licensed medical professionals only.
What are the Aesthefill specifications?
| Brand |
Aesthefill |
| Manufacturer |
REGEN Biotech, Inc. |
| Type |
PDLLA collagen stimulator, freeze-dried powder |
| Contents |
1 vial |
| Main ingredient |
Poly-D,L-lactic acid (PDLLA) microspheres |
| Storage |
Room temperature, away from light and moisture |
| Origin |
South Korea |
How does Aesthefill compare with Juvelook?
Both are PDLLA. Aesthefill goes deeper to rebuild structure, while Juvelook sits superficially to work on texture. Many clinics stock both.
For a PLLA alternative, see Power COL-TRA PLLA. PDLLA and PLLA work the same way, by triggering collagen, but the D,L form handles differently in the vial.
Frequently asked questions about Aesthefill
How long does the result last?
Practitioners commonly describe around 18 months to two years after a completed course.
Does it need refrigeration?
No. Keep the sealed vial at room temperature, away from light and moisture.
Is the result immediate?
No. Collagen builds gradually over the months after treatment.
Why order Aesthefill from Upkeep Skin?
Order Aesthefill here and you get competitive pricing, card payment and tracked express delivery from Seoul. In the US, we clear customs and cover the import tariffs, so there’s no bill on arrival.
The Shipping & Return tab lists delivery times by region. See other collagen biostimulators, including PDLLA products. Clinics can ask about wholesale pricing.
Shipping
Every order ships from Seoul by express courier with tracking. Shipping starts from $28 USD, and the exact cost is shown at checkout.
| Destination | Delivery time |
|---|
| United States | 2–4 business days |
| United Kingdom | 3–4 business days |
| Europe | 3–5 business days |
| Rest of the world | 3–5 business days |
USA orders: we handle customs clearance and pay the import tariffs for you, so there is nothing extra to pay on delivery.
Delivery times start once the order has been dispatched. Customs checks in some countries can occasionally add a day or two.
Payment
Pay securely by credit or debit card. Bank transfer is also available for larger and wholesale orders.
Returns
Because these are medical and professional products, we cannot accept returns once an order has shipped. If your order arrives damaged, defective or is not what you ordered, contact us within 7 days of delivery with photos of the box and product. We will send a replacement or refund you.
Questions about an order? Contact our team.
